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There are two image-related configuration options:
For the data processing it is important that the images appear in the HFS orientation. If this is not the case, either the HEAD FIRST or FEET FIRST option of Reorient to Standard Orientation should solve the problem. If not, please activate the with Operation button button during image loading and use the Assistance button to correctly HFS orient the PET study.
If the Set Acquisition Start Time to zero option is enabled, the start time of the first selected acquisition is set to zero, and the other frame times adjusted accordingly. This setting is highly recommended because due to DICOM compatibility issues the whole data may be shifted in time. In such a case, kinetic modeling will most likely not result in valid estimates.